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M. Sharon Stack

Dr. M. Sharon Stack received her PhD degree in Biochemistry from the University of Louisville, completed post-doctoral training in biochemical pathology at Duke University Medical Center, and served for several years as a Research Assistant Professor in Pathology at Duke.

In 1994, she joined the faculty in the Department of Cell & Molecular Biology at Northwestern University where she rose through the ranks to tenured Professor. While at Northwestern, Dr. Stack was also Program Leader of the Tumor Invasion, Metastasis and Angiogenesis Program of the NCI-designated RH Lurie Comprehensive Cancer Center (RHLCCC) and a member of the RHLCCC Executive Committee.

She joined the University of Missouri in 2007 as Professor and Vice Chair for Research in the Department of Pathology and Anatomical Sciences. She is currently (since 2011) Professor of Chemistry and Biochemistry and the Ann F. Dunne and Elizabeth Riley Director of the Harper Cancer Research Institute, University of Notre Dame.

Dr. Stack has served as a full member of the NIH/NCI Tumor Progression and Metastasis study section and on review panels for many other funding agencies, and is currently a member of the Department of Defense Ovarian Cancer Research Program (DOD OCRP) Integration Panel and Vision Setting Panel. [more]

Stack Lab Research Overview

The ability to invade host tissues and metastasize is the major cause of cancer-related death. During tumor invasion, metastasizing cells disrupt normal cell-cell and cell-matrix contacts and acquire a migratory, invasive phenotype. Thus modulation of cell-cell and cell-matrix adhesive events likely plays a critical role in tissue remodeling during tumor progression. Subsequent alterations in cellular architecture mediated by modified extracellular matrix (ECM) attachments induce expression of proteinases that degrade ECM proteins, facilitating migration through the modified tissue to establish metastatic foci and removing matrix constraints that normally limit proliferation. [more]


Partnerships and Collaborations


Harper Facebook

The University of Notre Dame Men's Rowing Ergathon is TODAY! Help spread the word and support them as they row for cancer research! You can donate to the cause here: app.mobilecause.com/vf/JOINTHEFIGHT/team/NDMensRowing #fightingirishfightingcancer #ergathon #goirishbeatcancer ...

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The University of Notre Dame and the Harper Cancer Research Institute will host the Harper Virtual Race from January 28 - February 3, 2018.

During this week, we’re challenging you to step away from the screen and engage in any form of physical activity—running, walking, rowing, swimming—to help raise money for the Harper Cancer Research Institute at Notre Dame. All proceeds from the race will go to the lifesaving work of the Harper Cancer Research Institute.

Thanks to gifts by the Walther Cancer Foundation and two generous Notre Dame families who have been touched by cancer, every dollar raised and mile (or mile equivalent) completed will be matched by $1 for the Harper Cancer Research Institute! (e.g. Joe Domer registers for $20 and runs 7 miles for Jane. Harper receives $27 in matching dollars in honor of Jane)

To register, visit giving.nd.edu/virtualrace.

For questions about format or registration, please email ndpride@nd.edu.

FAQs
-How do I sign up? Click donate above. In the confirmation email you will have the ability to create your own page and join/create a team!

-How do I log my activity? On January 28 you will be sent a link via email. On this site you will be able to log your miles and track our progress towards 10,000 miles!

-I've signed up but can't figure out how to join a team. Navigate to your personal page (the one you created through the form following your donation). Scroll to the bottom of the page and click "Edit" on the bottom right corner. From here you can further customize your page and join or create a team.

-I don't run. Can I still participate? Yes! All activity will count. Run, walk, bike, swim, row, etc. The week of January 28 you will be able to log your miles on this site. Prefer yoga, weight lifting, or some other activity? You can participate too! The form will include dozens of activities and provide mile equivalents for exercise.
...

HCRI Virtual Race

January 28, 2018, 12:00am - February 3, 2018, 11:59pm

The University of Notre Dame and the Harper Cancer Research Institute will host the Harper Virtual Race from January 28 - February 3, 2018. During this week, we’re challenging you to step away from the screen and engage in any form of physical activity—running, walking, rowing, swimming—to help raise money for the Harper Cancer Research Institute at Notre Dame. All proceeds from the race will go to the lifesaving work of the Harper Cancer Research Institute. Thanks to gifts by the Walther Cancer Foundation and two generous Notre Dame families who have been touched by cancer, every dollar raised and mile (or mile equivalent) completed will be matched by $1 for the Harper Cancer Research Institute! (e.g. Joe Domer registers for $20 and runs 7 miles for Jane. Harper receives $27 in matching dollars in honor of Jane) To register, visit giving.nd.edu/virtualrace. For questions about format or registration, please email ndpride@nd.edu. FAQs -How do I sign up? Click donate above. In the confirmation email you will have the ability to create your own page and join/create a team! -How do I log my activity? On January 28 you will be sent a link via email. On this site you will be able to log your miles and track our progress towards 10,000 miles! -I've signed up but can't figure out how to join a team. Navigate to your personal page (the one you created through the form following your donation). Scroll to the bottom of the page and click "Edit" on the bottom right corner. From here you can further customize your page and join or create a team. -I don't run. Can I still participate? Yes! All activity will count. Run, walk, bike, swim, row, etc. The week of January 28 you will be able to log your miles on this site. Prefer yoga, weight lifting, or some other activity? You can participate too! The form will include dozens of activities and provide mile equivalents for exercise.

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Human Papillomavirus
(HPV)-Associated
Oropharyngeal Cancer
(Hardcover & Kindle)

Daniel L. Miller (Editor)
M. Sharon Stack (Editor)
available on amazon.com


Ovarian Cancer book

Ovarian Cancer
Cancer Treatment and Research
(Hardcover)

M. Sharon Stack (Editor)
David A. Fishman (Editor)
available on amazon.com

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