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Refereed Journal Articles

Moss N.M., Barbolina M.V., Liu Y.,  Sun L., Munshi H.G., and Stack, M.S.  (2009) Ovarian Carcinoma Cell Detachment and Multi-cellular Aggregate Formation are Regulated by MT1-MMP:  A Potential Role in Intra-Peritoneal Metastatic Dissemination.  Cancer Research 69: 7121-9. PMCID: PMC2737080 [PDF]

Barbolina M.V., Adley B.P., Kelly D.L., Shepard J., Fought A.J., Scholtens D., Penzes P., Shea L.D. and Stack, M.S.  (2009) Downregulation of Connective Tissue Growth Factor by Three-Dimensional Matrix Enhances Ovarian Carcinoma Cell Invasion.  Int. J. Cancer 125:816-25. PMC2849282 [PDF]

Ghosh, S., Koblinski, J., Johnson, J., Liu, Y., Frazier, S., Ericcson, A., Shi, Z., Ravosa, M.J., Crawford, S., and Stack, M.S. (2010) Urinary-Type Plasminogen Activator Receptor (uPA/R)/a3b1 Integrin Signaling and Oral Tumor Progression.  Mol. Can. Res. 8: 145-158. PMCID: PMC2825738

Moss, N.M., Wu Y.I., Liu Y, Munshi H.G. and Stack M.S. (2009) Modulation of the Membrane Type 1 Matrix Metalloproteinase Cytoplasmic Tail Enhances Invasion and Proliferation in Three-Dimensional Collagen Matrices.  J. Biol. Chem 284, 19791-9.  PMCID:  PMC2740404 [PDF]

Moss, N.M., Liu, Y., Johnson, J.J., Debiase P., Jones J., Hudson, L.G., Munshi H.G.,  and Stack, M.S. (2009)  Epidermal Growth Factor Receptor-Mediated Membrane Type 1 Matrix Metalloproteinase Endocytosis Regulates the Transition Between Invasive and Expansive Growth in Three-Dimensional Collagen Mol. Can. Res. 7, 809-820.  PMCID:  PMC2843416 [PDF]

Woo, M., Salamanca C., Symowicz, J., Stack, M.S., Leung P., Gilks B., and Auersperg N. (2008) SV40 Early Genes Promote Neoplastic Progression of Serous Borderline Ovarian Tumors.  Gynecologic Oncology,111:  125-131. [PDF]

Adley, B.P., Gleason K., Yang, X. J., and Stack, M.S.  (2009) Expression of Membrane Type 1 Matrix Metalloproteinase (MMP-14) in Epithelial Ovarian Cancer:  High Level Expression in Clear Cell Carcinoma.  Gynecologic Oncology 112: 319-324. PMCID: PMC2663392 [PDF]

Pettus, J., Johnson, J.J., Shi, Z., Davis, J.W., Koblinski, J.K., Ghosh, S., Liu, Y., Ravosa, M.J., Frazier, S. and Stack, M.S. (2009) Multiple Kallikrein (5, 7, 8, and 10) Expression in Squamous Cell Carcinoma of the Oral Cavity.  Histology & Histopathology 24:197-207. PMCID: PMC2835693 [PDF]

Ravosa, M.J., López, E.K., Menegaz, R.A., Stock, S.R., Stack, M.S. & Hamrick, M.W. (2008) Using “Mighty Mouse” to understand masticatory plasticity: Myostatin-deficient mice and musculoskeletal function. Int. Comp. Biol. 48:345-359.

Wang C., Norton J.T., Ghosh S., Kim J.J., Fushimi K., Wu J.Y., Stack M.S. and Huang S. (2008)  PTB Differentially Affects Malignancy in a Cell Line Dependent Manner.  J. Biol. Chem. 283:  20277-87. [PDF]

Barbolina, M.V., Adley B.P., Kelly D.L., Fought A.J., Scholtens D., Shea L.D., and Stack, M.S. Motility Related Actinin Alpha-4 is Associated with Advanced and Metastatic Ovarian Carcinoma.  Laboratory Investigation 88, 602-614.  PMCID:  PMC2849305 [PDF]

Cowden-Dahl, K., Symowicz, J., Ning, Y., Gutierrez, E., Fishman, D.A., Adley, B.P., Stack, M. S. and Hudson, L.G. (2008)  Matrix Metalloproteinase-9 is a Mediator of Epidermal Growth Factor-Dependent E-cadherin Loss in Ovarian Carcinoma Cells.  Cancer Res 68, 4606-4613.  PMCID:  PMC2849305 [PDF]

Norton, J.T., Witschi M.A., Luong L., Kawamura A., Ghosh S., Stack, M.S., Sim E., Avram M.J., Appella D.H., Huang S. (2008)  Synthesis and Anticancer Activities of 6-amino Amonafide Derivatives.  Anticancer Drugs 19:23-36.

Barbolina, M.V., Adley, B.P., and Stack, M.S.  (2008) Wilms’ Tumor Gene Protein 1 is Associated with Ovarian Cancer Metastasis and Modulates Cell Invasion.  Cancer 112: 1632-41. NIHMSID127561 [PDF]

Wu, Y.I., Munshi, H.G., Snipas, S.J., Salvesen, G.S., Fridman, R., and Stack, M.S. (2007) Activation-Coupled Membrane Type 1 Matrix Metalloproteinase Membrane Trafficking.  Biochemical J. 407:171-7. [PDF]

Wolf, K., Wu, Y.I., Liu, Y., Tam, E., Geiger J., Brocker E.B., Overall C., Stack M. S. and Friedl P. (2007) Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion .  Nature Cell Biology 9:893-904. [PDF]

Do, T.V., Symowicz J.C., Berman D.M., Liotta L.A., Petricoin E.F. 3rd, Stack M.S. and Fishman D.A. (2007) Lysophosphatidic Acid Down-Regulates Stress Fibers and Up-regulates Pro-Matrix Metalloproteinase-2 Activation in Ovarian Cancer Cells.  Molecular Cancer Research 5:121-131. [PDF]

Symowicz, J.E., Adley, B.P., Gleason, K., Fishman, D.A., Hudson, L.G. and Stack, M.S.  (2007) Integrin Engagement Promotes Proteinase-Dependent E-Cadherin Ectodomain Shedding in Ovarian Carcinoma Cells.  Cancer Research 67: 2030-9. [PDF]

Barbolina, M.V., Ariztia, E.V., Adley, B.P., Liu, Y., and Stack, M.S.  (2007) Microenvironmental Regulation of Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Activity in Ovarian Carcinoma Cells via Collagen-Induced Egr-1 Expression. J. Biol. Chem. 282:4924-31. [PDF]

Ravosa, M.J., Kunwar, R., Stock, S.R. & Stack, M.S. (2007) Pushing the limit: Masticatory stress and adaptive plasticity in mammalian craniomandibular joints. J. Exp. Biol. 210:628-41. [PDF]

Ravosa, M.J., Kunwar, R., Nicholson, E.K., Klopp, E.B., Pinchoff, J., Stock, S.R., Stack, M.S. & Hamrick, M.W. (2006) Adaptive plasticity in mammalian masticatory joints. Developments in X-Ray Tomography V. 5th Proceedings of SPIE-Int. Soc. Optical Engineering 6318:1-9.

Ghosh, S., Johnson J.J., Sen, R., Mukhopadhyay S., Liu, Y., Zhang, F., Wei, Y., Chapman, H.A., and Stack, M.S.  (2006) Functional Relevance of Urinary-type Plasminogen Activator Receptor (uPAR)-alpha3beta1 Integrin Association in Proteinase Regulatory Pathways.  J. Biol. Chem.281:13021-9. [PDF]

Zeineldin R., Rosenberg M., Ortega D., Chavez M.G., Stack, M.S., Kusewitt D.F. and Hudson L.G. (2006)  Mesenchymal Transformation in Epithelial Ovarian Tumor Cells Expressing Epidermal Growth Factor Receptor Variant III.  Molecular Carcinogenesis 45:851-60. [PDF]

Ning, Y., Zeineldin, R., Liu, Y., Stack, M.S., and Hudson, L.G. (2005)  Downregulation of Integrin a2 Surface Expression by Mutant Epidermal Growth Factor Receptor (EGFRvIII) Induces Aberrant Cell Spreading and Focal Adhesion Formation.  Cancer Research 65:9280-6. [PDF]

Symowicz, J., Adley, B.P., Woo, M. M., Auersperg, N., Hudson, L.G., and Stack, M.S.  (2005) Cyclooxygenase-2 Functions as a Downstream Mediator of Lysophosphatidic Acid to Promote Aggressive Behavior in Ovarian Carcinoma Cells.  Cancer Research 65:2234-42. [PDF]

Graves, L.E., Ariztia, E.V., Navari, J.R., Matzel, H.J., Stack, M. S. and Fishman, D.A. (2004)  Proinvasive Properties of Ovarian Cancer Ascites-Derived Membrane Vesicles.  Cancer Research 64:7045-7049. [PDF]

Munshi, H.G., Wu Y.I., Mukhopadhyay S., Koblinski, J., Platanias L.C., and Stack M.S.  (2004) Transforming Growth Factor Beta1-Induced Pericellular Collagenolysis is Controlled Through Differential Regulation of Membrane-Type 1 Matrix Metalloproteinase Activity by Extracellular Signal-Regulated Kinase 1-2 and p38 Mitogen-Activated Protein Kinase.  J. Biol. Chem 279, 39042-39050. [PDF]

Lorch, J.H., Park, J.K, Klessner, J., Getsios, S., Stack, M.S. and Green, K.J.  (2004) Epidermal Growth Factor Receptor Inhibition Promotes Desmosome Assembly and Strengthens Intercellular Adhesion in Squamous Carcinoma Cells.  J. Biol. Chem.279:37191-37200. [PDF]

Mukhopadhyay, S.M., Munshi, H.G., Kambhampati, S., Sassano, A., Platanias, L.C. and Stack, M.S.  (2004) Calcium Induced Matrix Metalloproteinase-9 Gene Expression is Differentially Regulated by ERK1/2 and p38 MAPK in Oral Squamous Cell Carcinoma. J. Biol. Chem., 279:33139-33146. [PDF]

Tam, E.M., Morrison, C.J., Wu, Y.I., Stack, M.S., and Overall, C.M. (2004) Membrane Protease Proteomics: Isotope Coded Affinity Tag/Tandem Mass Spectrometry Identification of Novel MT1-MMP Substrates.  Proc. Nat. Acad. Sci. 101:6917-6921. [PDF]

Wu, Y.I., Munshi, H.G., Sen, R., Snipas, S.J., Salvesen, G.S., Fridman, R., and Stack, M.S.  (2004) Glycosylation Broadens the Substrate Profile of Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) J. Biol. Chem. 279:8278-8289. [PDF]

Lauer-Fields, J.L., Sritharan, T., Stack, M.S., Nagase, H., and Fields, G.B.  (2003) Selective Hydrolysis of Triple-Helical Substrates by Matrix Metalloproteinase-2 and -9.  J. Biol. Chem. 278:18140-18145. [PDF]

Munshi, H.G., Wu, Y.I., Ariztia, E.A. and Stack, M.S. (2002) Calcium Regulation of Matrix Metalloproteinase-2-Mediated Migration in Oral Squamous Cell Carcinoma.  J. Biol. Chem. 277: 41480-41488. [PDF]

Tam, E., Wu, Y.I., Butler, G.S., Stack, M.S. and Overall, C.M.  (2002) Collagen Binding Properties of the MT1-MMP Hemopexin C Domain: The Ectodomain of the 44 kDa Autocatalytic Fragment of MT1-MMP Inhibits Cell Invasion by Disrupting Native Type I Collagen Cleavage.  J. Biol. Chem. 277:39005 [PDF]

Munshi, H.G., Ghosh, S., Mukhopadhyay, S., Wu, Y.I., Sen, R., Green, K.G., and Stack, M.S.  (2002) Proteinase Suppression by E-Cadherin-Mediated Cell-Cell Attachment in Premalignant Oral Keratinocytes.  J. Biol. Chem., 277:38159-38167. [PDF]

Ghosh, S., Munshi, H.G., Sen, R., Linz-McGillem, L.A., Goldman, R.D., Lorch, J., Green, K.J., Jones, J.C.R. and Stack, M.S. (2002) Loss of Adhesion-Regulated Proteinase Expression in Oral Squamous Cell Carcinoma.  Cancer 95:2524-2533. [PDF]

Mauceri, H.J., Seetharam, S., Beckett, M.A., Lee, J.Y., Gately, S., Stack, M.S., Brown C.K., Swedberg, K., Gupta, V.K., Kufe, D.W., and Weichselbaum, R.R. (2002) Tumor Production of Angiostatin is Enhanced After Exposure to TNF-alpha .  Int. J. Cancer 97:410-415. [PDF]

Bannon, L.J., Cabrera, B.L., Stack, M. S. and Green, K.J. (2001)  Isoform-Specific Differences in the Size of Desmosomal Cadherin/Catenin Complexes.  J. Invest. Derm. 117:1302-1306.

Bannon, L.J., Stack, M.S., and Green, K.J. (2001) Limitation of Comparative Detection of Proteins via Epitope Tagging. Anal. Biochem. 293:139-42. [PDF]

Ellerbroek, S.M., Wu, Y., Overall, C.M. and Stack, M.S. (2001) Functional Interplay Between Type I Collagen and Cell Surface Matrix Metalloproteinase Activity. J. Biol. Chem. 276:24833-42. [PDF]

Ellerbroek, SM, Wu, Y.I., and Stack, M.S. (2001) Type I Collagen Stabilization of Matrix Metalloproteinase-2. Arch. Biochem. Biophys. 390:51-56 [PDF]

Fishman, D.A., Liu, Y., Ellerbroek, S.M. and Stack, M.S.  (2001) Lysophosphatidic Acid Promotes Matrix Metalloproteinase Processing and MMP-Dependent Invasion in Ovarian Carcinoma Cells.  Cancer Research 61, 3194-3199. [PDF]

Ellerbroek, S.M., Halbleib, J., Benevidez, M., Wattenbeg, E.V., Stack, M.S. and Hudson, L.G.  (2001) Requirement for Phosphatidylinositol 3-Kinase Activity in Epidermal Growth Factor-Stimulated Matrix Metalloproteinase (MMP)-9 Production and Cell Surface Association. Cancer Research 61: 1855 [PDF]

Rao, C.N., Reddy, P., Reeder, D.J., Liu, Y., Stack, S., Kisiel, W., and Woodley, D.T. (2000) Prokaryotic Expression, Purification, and Reconstitution of Biological Activities (Antiprotease, Antitumor, and Heparin-Binding) for Tissue Factor Pathway Inhibitor-2.  Biochem. Biophys. Res. Commun.276, 1286-1294.

Rodriguez, G.C., Haisley, C., Hurteau, J. Moser, T.L., Whitaker, R., Bast, R.C., Jr. and Stack, M.S. (2000) Regulation of Invasion of Epithelial Ovarian Cancer by Transforming Growth Factor Beta.  Gynecologic Oncology 80:245-253. [PDF]

Goldfinger, L.E., Hopkinson, S.B., Stack, M.S., and Jones, J.C.R. (2000) Spatial Regulation and Affinity Modulation of Plasmin by High-Affinity Binding to the G Domain of the  3 Subunit of Laminin-5.  J. Biol. Chem. 275:34887-93. [PDF]

Ghosh, S., Brown, R., Jones. J.C.R., Ellerbroek, S.M. and Stack, M.S. (2000) Urinary-Type Plasminogen Activator (uPA) Expression and uPA Receptor Localization Are Regulated by alpha3beta1 Integrin in Oral Keratinocytes. J. Biol. Chem. 275:23869-23876.


Book Chapters and Invited Reviews

Hudson, L.G., Moss, N.M., and Stack, M. S.  (2009) Epidermal Growth Factor Receptor Regulation of Matrix Metalloproteinases in Epithelial Ovarian Carcinoma.  Future Oncology 5:323-38. PMCID: PMC2709955 [PDF]

Hudson, L.G., Zeineldin, R., Silberberg, M. and Stack, M.S. (2009) Activated EGF Receptor in Ovarian Cancer; in Ovarian Cancer; Stack M.S. and Fishman, D.A., Editors.  Springer, 203-228.

Barbolina, M.V., Moss, N.M., Westfall, S.D., Liu Y., Burkhalter, R.J., Marga, F., Forgacs, G., Hudson, L.G. and Stack, M.S. (2009) Microenvironmental Regulation of Ovarian Cancer Metastasis, in Ovarian Cancer; Stack M.S.and Fishman,D.A., Editors. Springer, 319-334 [PDF]

Hudson, L.G., Zeineldin, R., and Stack, M.S. (2008)  Phenotypic Plasticity of Neoplastic Ovarian Epithelium:  Unique Cadherin Profiles in Tumor Progression.  Clin. Exp. Metastasis, 25:  643-55. PMCID:  PMC2836537 [PDF]

Barbolina, M. and Stack, M.S.  (2008) Membrane Type-1 Matrix Metalloproteinase:  Substrate Diversity in Pericellular Proteolysis. W. Parks, Ed. Seminars in Cell and Develop. Biol., 19:24-33. PMCID: PMC2685078 [PDF]

Ravosa, M.J., López, E.K., Menegaz, R.A., Stock, S.R., Stack, M.S. & Hamrick, M.W. (2008) Adaptive plasticity in the mammalian masticatory complex: You are what, and how, you eat. C.J. Vinyard, M.J. Ravosa & C.E. Wall (Eds.): Primate Craniofacial Biology and Function. New York: Springer Academic Publishers, pp. 293-328.

Shi, Z., and Stack, M.S. (2007) Urinary-Type Plasminogen Activator (uPA) and its Receptor (uPAR) in Oral Squamous Cell Carcinoma of the Oral Cavity.  Biochemical Journal 407:  153-9. [PDF]

Munshi, H.G. and Stack, M.S.  (2006) Reciprocal Interactions Between Adhesion Receptor Signaling and MMP Regulation, for Cancer Metastasis Reviews  25: 45-56. [PDF]

DeClerck, Y.A., Mercurio, A.M., Stack, M.S., Chapman, H.A., Zutter, M.M., Muschel, R.J., Raz, A., Matrisian, L.M., Sloane, B.F., Noel, A., Hendrix, M.J., Coussens, L., and Padarathsingh, M. (2004) Proteases, Extracellular Matrix,and Cancer:a workshop of the path B study section.  Am. J. Pathol. 164:1131-1139. [PDF]

H.G. Munshi and M. Sharon Stack (2002) Analysis of Matrix Degradation in Methods in Cell Biology 69: 195-205, Methods in Cell-Matrix Adhesion, Academic Press, San Diego. [PDF]

Moser, T.L., Stack, M.S., Wahl, M.L., and Pizzo, S.V. (2002) The Mechanism of Action of Angiostatin, Thrombosis and Haemostasis 87:394-401.

Ellerbroek, S.M., Wu, Y., and Stack, M.S. (2002)  Regulatory Mechanisms for Proteinase Activity, in Proteinase and Peptidase Inhibition: Recent Potential Targets for Drug Development, Smith, H.J.  and Simons, C.eds.,Taylor and Francis, London, pp.210958

Stack, M.S. (2001) Matrix Metalloproteinases, in Cancer: An Encyclopedic Reference, Springer Verlag, in press.

Mills, G.B., Eder, A, Fang, X., Hasegawa, Y., Mao, M., Lu, Y., Tanyi, J., Tabassam, F.H., Wiener, J., Lapushin, R., Yu, S., Parrott, J.A., Compton, T., Tribley, W., Fishman, D., Stack, M.S., Gaudette, D., Jaffe, R., Furui, T., Aoki, J., Erickson, J.R. (2001) Critical Role of Lysophospholipids in the Pathophysiology, Diagnosis, and Management of Ovarian Cancer, in Cancer Treatment and Research: Ovarian Cancer, Stack, M.S. and Fishman, D.A., Editors Kluwer Academic Publishers, pp 259-284.

Ghosh, S., Wu, Y., and Stack, M.S. (2001) Ovarian Cancer-Associated Proteinases, in.  Cancer Treatment and Research: Ovarian Cancer, Stack, M.S. and Fishman, D.A., Editors Kluwer Academic Publishers, pp.331-351.

Ghosh, S. and Stack, M.S. (2000) Structural and Functional Modifications of Laminins by Proteolytic Cleavage.  Microscopy Research and Technique 51:238-246.

Ghosh, S., Wu, Y., Ellerbroek, S.M., and Stack, M.S. (2000) Tumor Cell Mediated Proteolysis: Regulatory Mechanisms and Functional Consequences.  Fibrinolysis and Proteolysis 14:87-97.


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